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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHAT
All Species:
0.61
Human Site:
S279
Identified Species:
1.11
UniProt:
P28329
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28329
NP_066266.3
748
82536
S279
Q
Y
Y
G
L
F
S
S
Y
R
L
P
G
H
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109211
626
70697
K195
D
T
V
S
N
F
S
K
T
K
K
P
P
T
H
Dog
Lupus familis
XP_543902
686
76910
V255
N
Q
F
F
V
L
D
V
V
I
N
F
R
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q03059
641
71834
V210
N
Q
F
F
V
L
D
V
V
I
N
F
R
R
L
Rat
Rattus norvegicus
P32738
640
71845
V209
N
Q
F
F
V
L
D
V
V
I
N
F
R
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509108
643
72737
V212
N
Q
F
F
V
L
D
V
V
I
N
F
R
R
L
Chicken
Gallus gallus
Q90YJ9
640
72605
V209
N
Q
L
F
V
L
D
V
G
I
N
F
R
R
L
Frog
Xenopus laevis
Q7ZXE1
659
74538
I228
R
L
F
N
C
T
R
I
P
K
P
N
R
D
E
Zebra Danio
Brachydanio rerio
B2ZGJ1
637
71821
V206
F
F
V
L
D
V
M
V
N
F
R
R
L
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07668
721
81310
Y271
V
I
C
R
N
Q
M
Y
C
V
V
L
Q
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P32756
627
71299
N196
H
V
L
V
M
C
R
N
Q
T
F
L
L
H
S
Sea Urchin
Strong. purpuratus
XP_001185550
675
75787
I244
F
F
I
L
D
V
I
I
N
F
K
R
L
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32796
670
77223
V239
D
T
N
I
F
Y
S
V
Y
E
N
N
F
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
37.8
77.9
N.A.
74.7
74.7
N.A.
68.4
66
24
57
N.A.
37.5
N.A.
29.2
46.3
Protein Similarity:
100
N.A.
55.7
82.4
N.A.
79.1
79
N.A.
76.5
74
40.6
68.8
N.A.
56.1
N.A.
45.1
62.4
P-Site Identity:
100
N.A.
20
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
N.A.
26.6
13.3
N.A.
13.3
13.3
N.A.
13.3
6.6
20
13.3
N.A.
13.3
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
8
0
8
8
0
0
8
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
16
0
39
0
0
0
0
0
0
8
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
16
% E
% Phe:
16
16
39
39
8
16
0
0
0
16
8
39
8
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
8
0
0
0
8
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
16
8
% H
% Ile:
0
8
8
8
0
0
8
16
0
39
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
16
16
0
0
0
0
% K
% Leu:
0
8
16
16
8
39
0
0
0
0
8
16
24
0
39
% L
% Met:
0
0
0
0
8
0
16
0
0
0
0
0
0
0
0
% M
% Asn:
39
0
8
8
16
0
0
8
16
0
47
16
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
8
16
8
0
0
% P
% Gln:
8
39
0
0
0
8
0
0
8
0
0
0
8
0
0
% Q
% Arg:
8
0
0
8
0
0
16
0
0
8
8
16
47
39
0
% R
% Ser:
0
0
0
8
0
0
24
8
0
0
0
0
0
8
16
% S
% Thr:
0
16
0
0
0
8
0
0
8
8
0
0
0
8
16
% T
% Val:
8
8
16
8
39
16
0
54
31
8
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
8
0
8
16
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _